AI × BIOPROCESS

A world model for biomanufacturing

Grounded in the physics and biology of cell culture. Simulate how a process will behave before you run it, from the first experiment to the commercial plant. Fewer experiments in the lab. Fewer surprises in production.

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R&D

Most development discovers by running experiments. Ark simulates first and only experiments where the model’s knowledge runs out. Each run updates it. You reach IND faster, with a process robust enough to hold at commercial scale.

Manufacturing

Ark runs a live digital twin of your facility, continuously simulating how every batch should behave. An army of agents monitors your plant around the clock: catching deviations at the first signal, recommending mitigations, and surfacing opportunities to improve yield and uptime. Your team makes the call.

How Ark drives results

43% above the program’s best-ever titer, first run

Real-time optimization surfaced feed strategy adjustments mid-run as the process crossed into uncharted territory. The result: a new record.

Case Study

40% fewer experiments in process development

A development program used model-based DoE to reduce experimentation by 40%. Each run was designed to maximize learning or provide experimental validation for regulators.

110% higher yield than statistical DoE

Model-based DoE plus in silico optimization more than doubled yield, and matched the statistical best in one-third fewer experiments.

Best titer ever for a blockbuster drug

Post-licence optimization with ambr250 scale-down modeling let the team test new strategies safely at bench scale.

Digital Twin on a high-variability commercial process

A commercial process with high run-to-run variability runs Ark’s Digital Twin to reduce manufacturing variability.

Scale-up predicted before the first commercial batch

A development team used Ambr 250 data to quantify process performance at 15,000 L and determine the control strategy needed to match it. Tech transfer first-time-right.

Trusted by Scientists

A virtual bioreactor run,

‍in seconds

Use Ark's software to enhance decision-making from early-stage process development to commercial manufacturing.

Shorten timelines

Experiment 1,000x faster. Simulate thousands of experiments in parallel to optimize your process, ensure robustness, and scale up first time right.

Run fewer experiments

Minimize bioreactor runs by testing hypotheses in silico. Only conduct physical experiments when truly needed to push the boundaries of knowledge.

Improve outcomes

Optimize critical process parameters leveraging direct insights from advanced simulations. Improve titer and overall process robustness.

Run virtual experiments. Deepen process understanding.

Turbocharge insights with Ark’s comprehensive collection of 25+ cell culture trends — from growth metrics like titer, viability, and VCD to metabolic indicators like pCO₂, lactate, and ammonia, plus soft sensors such as impeller and sparger P/V.

Because simulations run in seconds, you can generate deeper insights faster than with physical bioreactors — from rapid sensitivity analyses to full factorial DOEs.

In silico optimization. Find the best recipe, faster.

Explore tens of thousands of process variations with a single click. Set your goals and constraints, and Ark will rank and compare recipes to reveal the optimal path forward.

Leverage optimization across lifecycle from pre-IND through commercial scale to maximize yield, minimize variability, and ensure every run performs at the highest level.

Scale up, first time right.

Quantify cell culture performance across scales and configurations using a dynamic and comprehensive bioreactor model.

Analyze quantitative trends, such as pCO2 and osmolality, across scales to identify, evaluate, and address potential challenges early.

Facilitate balanced decision-making under complex constraints to drive success.

Simulation made easy.

Get started with Ark in minutes — no coding, no special data requirements. Simply upload the experimental data you already generated and create a custom model instantly.

With low activation energy, any scientist can start simulating right away. From experiment to in silico insights has never been this simple.

Deepen insights with your own

‍Bioprocess AI Assistant

Access and interpret results through an interactive chatbot—putting clear, actionable insights right at your fingertips.

AI × Bioprocess

Bioprocess is too complex and too data-scarce for AI to learn from examples alone. The only path to a model that generalizes is to start from what science already knows: the physics. Ark’s world model encodes the multiphysics of bioprocess—mass transfer, cell growth kinetics, chemical reactions—and uses your process data to close the gaps where physics runs out.

Physics handles what can be computed from first principles. Data sharpens the model where it can’t. The result works across scales and cell lines, can simulate what hasn’t been run yet, and gets more accurate with every batch.

Built for regulated environments and sensitive data

Audit trail, built in

Every recommendation and decision is logged, consistent with 21 CFR Part 11 and EU Annex 11.

Your data stays yours

Hosted in a single-tenant environment and never used to train models across companies.

SOC 2 Type II certified

Independently audited security controls, monitored continuously.

Encrypted and access-controlled

AES-256 at rest, TLS in transit, with strict usage and permission controls.

Put the world model to work

on your process

Partner with Ark

AI × BIOPROCESS

A world model for biomanufacturing

A virtual bioreactor run,

‍in seconds

Shorten timelines

Run fewer experiments

Improve outcomes

Run virtual experiments. Deepen process understanding.

In silico optimization. Find the best recipe, faster.

Scale up, first time right.

Simulation made easy.

Deepen insights with your own

‍Bioprocess AI Assistant

How it Works

Software designed by scientists, for scientists

Support bioprocess life cycle

Generate value, even with limited data

Bioreactor agnostic

Data Security

Designed to protect your data

SOC 2 Type II certified for secure, reliable, and compliant operations

Data encryption

Secure hosting

Strict permission controls

Strict usage controls

Version control and software updates

Secret management

Put the world model to work

on your process

TEchnology

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(857)-957-7498

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